The evolution of intraocular lenses (IOLs) represents one of the most transformative advancements in ophthalmic surgery.
From the earliest attempts to restore vision through primitive cataract couching techniques to the refined art of modern phacoemulsification with lens implantation, the journey has been marked by continuous innovation and material science breakthroughs.
A look back at intraocular lenses
The pivotal moment came with Sir Harold Ridley’s observation during World War II that fragments of PMMA (polymethyl methacrylate) from cockpit canopies remained inert in the eyes of injured pilots.1,2 This discovery laid the foundation for the world’s first successful IOL implantation in 1949, marking the dawn of a new era in cataract surgery.
Following Ridley’s pioneering work, advancements in IOL materials and design have continually enhanced surgical outcomes and patient safety—from rigid PMMA lenses to foldable silicone and acrylic IOLs to hydrophobic and hydrophilic options.
Today, the availability of multifocal, accommodative, and extended depth-of-focus IOLs reflects the sophistication of optical engineering aimed at achieving spectacle independence. Innovations continue to push the boundaries of refractive cataract surgery. As a presbyopia-correcting IOL with advanced diffractive optics, the TECNIS Odyssey represents one of the most significant advancements.
Its design eliminates traditional gaps between near, intermediate, and distance vision to offer a continuous visual experience. In this article, Caroline Watson, MD, offers her perspective on implementing and implanting this device.
What are the benefits of the TECNIS Odyssey in your opinion?
In my early experience, a standout feature of the Odyssey has been its enhanced tolerance to residual refractive error.3 This has made outcomes more consistent and broadened candidacy.
For my patients, visual recovery is rapid and reliable. Patients often achieve both near and distance vision goals by Day 1 or Week 1 post-op. Bothersome dysphotopsia complaints are minimal compared to earlier generations—93% of patients in a recent study reported no or mild glare, halos, or starbursts at 1 month.4
For which patient is the TECNIS Odyssey best suited?
The TECNIS Odyssey is suitable for cataract patients with healthy eyes. I avoid it in those with severe maculopathy, untreated ocular surface disease, advanced glaucoma, or prior radial keratotomy. In Huntsville, Alabama—home to many engineers, scientists, and pilots—I’ve found that even patients with high visual demands and “Type A” personalities do well with this lens.
Surgical pearls for success
- Pre-operative optimization of the ocular surface is critical. My protocol includes preservative-free tears, lash hygiene (Dr. Ashley Brissette’s Daily Practice cleanser), and warm compresses (Bruder mask).
- Based on patient needs, I may also prescribe XDEMVY (0.25% lotilaner ophthalmic solution, Tarsus Pharmaceuticals) or OXERVATE (cenegermin-bkbj ophthalmic solution 0.002% [20 mcg/mL], Dompé), use amniotic membranes, or perform LipiFlow.
- I tell patients the Odyssey can provide spectacle independence for over 90% of daily tasks—driving, screen use, TV, hunting—while some may need readers for fine detail work.
- For new users, consider a mix-and-match approach, starting with implantation in the nondominant eye.
Final thoughts
The rapid progression of IOL technology underscores ophthalmology’s commitment to refining both surgical precision and patient quality of life. As devices like the TECNIS Odyssey continue to bridge the gap between functional vision and optical perfection, surgeons are empowered to deliver outcomes once thought unattainable.
With innovations that expand candidacy, improve visual recovery, and minimize photic phenomena, the future of refractive cataract surgery looks exceptionally bright. Ultimately, ongoing collaboration between clinicians, engineers, and industry partners will continue to redefine what’s possible for our patients’ vision.
