Published in Ocular Surface

Asymptomatic Dry Eye Diagnosis Requires Some Detective Work

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5 min read

When inspecting a patient for dry eye, refraction, slit lamp exams, and meibography provide optometrists with the evidence needed to close the case.

Asymptomatic Dry Eye Diagnosis Requires Some Detective Work
When patients make an appointment for an annual eye exam, they inevitably have questions about their vision. So often, patients look to their eyecare professional to tell them they are ready for new glasses, but there may be other hidden eye health conditions that only a comprehensive eye exam can uncover.
A little detective work may reveal that a patient has asymptomatic dry eye, a multifactorial and progressive disease that, if left untreated, can have debilitating effects.
A thorough screening can identify and stop this disease before symptoms can even be detected. I see patients of all ages. More of my younger patients are diagnosed with severe dry eye disease, while my geriatric patients seem to have fewer struggles with the condition. Recent studies show that, while many factors contribute to dry eye, eye strain from screen usage plays a big part.1 Fortunately or not, our dependence on screens is here to stay.

Building your optometrist detective toolkit

A patient’s lifestyle and environment can also contribute to dry eye, so eyecare professionals have to be willing to play the part of the detective by performing comprehensive screenings, even for asymptomatic patients, to stop conditions like dry eye disease in its earliest stages.

Start your investigation with refraction

This foundational exercise helps to measure visual acuity, but also gives providers the opportunity to ask a few probing questions to assess the health of the ocular surface. When patients tell me that they see a bit more clearly after they blink, my sleuthing instincts tell me that there is an ocular surface issue at play.
This puzzle piece not only tells me how well the patient is seeing, but also how their eyes are feeling. An eye that sees and feels better after a blink is often one that is dry. Patients often say that their eyes feel tired and chalk it up to aging or lack of sleep, not realizing that if your eyes are healthy, then you likely won’t notice them at all.

Use a slit lamp to gather clues

Every good detective needs a solid tool to get to the truth of the case, and the slit lamp is my lie detector. When I use it, my patients suddenly tell me everything and admit to habits that can exacerbate dry eye, such as not properly cleansing the lid of cosmetics and any behaviors that mask symptoms, like the overuse of over-the-counter drops.
Lifestyle choices and habits are important pieces to the puzzle. Long stretches of time staring at screens, poor hygiene, and using certain cosmetic products can exacerbate dry eye, even if the patient is not feeling symptoms.

Conduct meibography to close the case

If the first two tests are pointing to asymptomatic dry eye disease, meibography reveals the severity and type. Meibography shows the status of the meibomian glands in the lower and upper eyelids. It’s important to note that meibomian glands that are gone or not working well lead to tear film instability, meaning they are not providing the oil layer that helps us see clearly and comfortably. Without that oil layer spread over the eye, with each blink redness, irritation, blurry vision, and if left untreated, corneal damage can occur.
Damaged meibomian glands are probably the most important piece to the puzzle since, once damaged or destroyed, these glands cannot properly produce healthy meibum. This has become an important tool in my practice because, when all else fails, it reveals so much about a patient’s eye health and the quality of the tear film. A patient may be asymptomatic, but meibography will reveal if damage is occurring.


These three pieces to the puzzle give a thorough look at each patient’s ocular surface. Patients with good vision do not necessarily have healthy eyes. We have the tools to learn much about each patient’s eyes and vision, but it is up to us to put the pieces together.
As we learn more about dry eye disease, we also have tools to put together a personalized treatment plan for patients. A little detective work implemented into an annual exam helps eyecare providers be proactive instead of reactive in treating dry eye, even before symptoms emerge.
  1. Al-Mohtaseb Z, Schachter S, Shen Lee B, Garlich J, Trattler W. The Relationship Between Dry Eye Disease and Digital Screen Use. Clin Ophthalmol. 2021 Sep 10;15:3811-3820. doi: 10.2147/OPTH.S321591. PMID: 34531649; PMCID: PMC8439964.
Inna Lazar, OD
About Inna Lazar, OD

Dr. Lazar obtained her Doctor of Optometry Degree from the Pennsylvania College of Optometry, now known as Salus University. Dr. Lazar’s clinical training includes diagnosing and managing ocular diseases, specialty contact lens fittings, pediatric and geriatric eye exams, and comprehensive primary eye care.

She received her training at numerous hospitals throughout the United States, including The Eye Institute in Philadelphia, the Einstein Hospital in Philadelphia, Ophthalmic Consultants of Connecticut in Fairfield, and Kay, Tabas & Niknam Ophthalmology Associates in Philadelphia.

She is a member of the American Optometric Association, the American Academy of Optometry, and the Connecticut Optometric Association. Dr. Lazar especially enjoys working with children and has participated in the volunteer Head Start program, providing initial screenings and eye exams to children in Philadelphia.

Inna Lazar, OD
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