Published in Retina

Going Solo in Retina: A Practical Guide to Launching an Independent Practice

This is editorially independent content
5 min read

Join Dr. Rishi Singh as he hosts a discussion on the considerations and challenges surrounding solo practice ownership with Dr. Louis Cai.

Disclaimer: The views expressed in this video and article are those of Dr. Cai, who emphasized that there are many ways to be successful in launching a solo retina practice.

One of the most important career decisions ophthalmologists face is which practice setting would best serve their priorities, personality, and long-term goals. For some, academia is the answer. Others opt for a hospital or group setting. Then there are clinicians, like Louis Cai, MD who follow the path of solo practice ownership.

I knew I didn't fit the mold that a lot of private practices and private equity practices offered me, so I decided to go on my own and try to do my own thing, primarily for control over my work-life balance.

In this episode of Evidence Based Retina, Rishi Singh, MD, FASRS, learns the reasoning behind this decision and gleans practical advice on going solo.

Location, location, location

Choosing where to open a solo retina practice determines whether referring optometrists and comprehensive ophthalmologists send patients there at all.
National provider-distribution data show ophthalmology practice locations have expanded faster than the ophthalmologist workforce itself, narrowing the average distance between an optometrist's office and the nearest ophthalmology practice to 11 miles.1 A practice sited near a dense cluster of referring providers, and away from an established retina competitor, starts with a structural referral advantage instead of building one from scratch.
Location carries clinical weight too. A Cole Eye Institute cohort of 642 retinal detachment repairs found reattachment rates were statistically similar regardless of travel distance, but longer travel was tied to delays before surgery.2
Moreover, a 2022 American Academy of Ophthalmology review found comparable geographic and travel-related access gaps affecting outcomes in glaucoma, cataract, and diabetic retinopathy care, with exam adherence dropping once patients live roughly 80 miles or more from a facility.3 For a retina practice serving an older, sight-threatened population, minimizing that travel burden is part of the care plan.

To learn more about leading a retina practice, check out: Hurdles for Modern Retina Practices: Rural Eyecare, Private Equity, and Hiring!

Using AI to identify optimal practice locations

Cai's approach turns this into a repeatable process rather than a gut call. He builds a custom map of every retina specialist, optometrist, and comprehensive ophthalmologist in a target region—red, blue, and green pins, respectively—then uses artificial intelligence (AI) to identify the spot with the greatest concentration of comprehensive ophthalmologists and optometrists and the greatest distance from the nearest retina specialist.
Critically, he runs that analysis on driving distance rather than straight-line mileage, since a 10-mile radius means something very different in Massachusetts traffic than on a rural Florida highway. Once the target area is set, he shifts to commercial real estate listings to evaluate specific properties, aiming for at least 1,200 to 1,300 square feet at minimum, with room to grow if the practice adds an associate down the line.
For the office itself, Cai draws a clear line between must-haves and nice-to-haves: two exam lanes with a connecting flow between them, and a dedicated room for injections, are non-negotiable starting points for a new retina practice.

Establishing essential equipment

“There’s always a balance between what you know, what’s cheapest, and what’s best. What you buy is going to need to last ideally the life of your practice,” explained Dr. Cai. “While buying used for certain items makes sense, I’d encourage you to invest in things that can affect patient outcomes,” he added. When opening an ophthalmology practice, it is essential to prioritize which equipment is most necessary for success.

Ultimately I want to be in a practice where I feel I have all the tools I need to do the best care.

For Dr. Cai, priority was directly correlated with price. Therefore, he approached the decision by buying the more expensive equipment first: fundus cameras and optical coherence tomography (OCT). After the biggest ticket items, he turned his focus to purchasing a pattern laser for panretinal photocoagulation (PRP), for the treatment of diabetic retinopathy and retinal vein occlusions.
After researching the available options, he chose the battery-powered Norlase LYNX—the first and only pattern scanning laser indirect ophthalmoscope.4 "Norlase has the most modern viewing system, and it’s readily portable. Having the pattern feature makes it the only one of its kind, and I had to splurge," he explained.

Takeaways

  • A retina practice requires a minimum of 1,200 to 1,300 square feet, two exam lanes, a dedicated injection room, and an OCT as non-negotiable equipment.
  • Joining a group purchasing organization (GPO) allows independent retina specialists to negotiate better drug pricing than purchasing directly from distributors.
  • EHR systems for a new ophthalmology practice range from $600 to $2,000 per month and typically bundle practice management, scheduling, and documentation software.
  • Securing net-30, net-60, or net-90 repayment terms with drug suppliers is critical to managing cash flow while awaiting insurance reimbursement.
  • AI tools like ChatGPT and Gemini are now being used by independent physicians to navigate administrative tasks, site selection, and practice logistics from day one.

Conclusion

Solo practice ownership demands tolerance for uncertainty and a willingness to wear every hat in the early phase—but Dr. Cai's experience shows the path is viable.
With deliberate site selection, disciplined equipment prioritization, GPO partnerships, and AI-assisted administrative workflows, an independent retina practice can be built on a manageable foundation.
For ophthalmologists evaluating referral relationships or their own career trajectory, understanding what goes into building a solo retina practice offers practical professional context.
  1. Kastl PR, Senot C, Hegde R. Distribution of ophthalmologists and optometrists in the United States. JAMA Ophthalmol. 2026;144(1):107-108.
  2. Rahman S, Russell MW, Joo JH, Valentim CCS, Singh RP. The impact of travel distance on rhegmatogenous retinal detachment presentation and outcomes. Ophthalmic Surg Lasers Imaging Retina. 2022;53(12):666-672.
  3. Solomon SD, Shoge RY, Ervin AM, et al. Improving access to eye care: a systematic review of the literature. Ophthalmology. 2022;129(10):e114-e126.
  4. Pattern Scan Laser: Modern Technology For Ophthalmologists. Norlase. February 6, 2023.https://norlase.com/pattern-scan-laser/.
Rishi P. Singh, MD, FASRS
About Rishi P. Singh, MD, FASRS

Rishi P. Singh, MD, FASRS, is the Chair of the Department of Ophthalmology at Mass General Brigham, overseeing ophthalmology across Massachusetts Eye and Ear, Massachusetts General Hospital, Brigham and Women’s Hospital, and affiliated sites. He is also a Professor of Ophthalmology at Harvard Medical School.

Previously, Dr. Singh served as Vice President and Chief Medical Officer at Cleveland Clinic Martin Health in Stuart, Florida, and as a staff surgeon at the Cleveland Clinic, where he was also Professor of Ophthalmology at the Cleveland Clinic Lerner College of Medicine in Cleveland, Ohio. He received both his undergraduate degree in medical science and his medical degree from Boston University, completing his internship at Tufts University. Dr. Singh went on to complete his ophthalmology residency at the Massachusetts Eye and Ear Infirmary/Harvard Medical School and a medical and surgical vitreoretinal fellowship at the Cole Eye Institute at the Cleveland Clinic.

Dr. Singh specializes in the management of complex retinal diseases, including diabetic retinopathy, retinal vein occlusions, retinal detachment, and age-related macular degeneration. He has authored over 300 peer-reviewed publications, books, and book chapters and serves as Principal Investigator for numerous national and international clinical trials aimed at improving outcomes for patients with retinal diseases.

He is the founder and past president of the Retina World Congress, chairs some of the largest continuing medical education meetings in retina, and serves on editorial boards and review panels for major ophthalmology journals. His leadership has extended into digital innovation, having helped lead enterprise-wide implementation of clinical technologies including Epic modules, digital informed consent, and patient-facing kiosks.

Dr. Singh has received multiple accolades for his contributions to ophthalmic research and innovation, including the Alpha Omega Alpha Research Award, the American Society of Retina Specialists Young Investigator Award, and the J. Donald Gass Beacon of Sight Award. He also leads The Center for Ophthalmic Bioinformatics, a research initiative focused on leveraging big data and artificial intelligence to advance understanding and treatment of retinal disease.

Rishi P. Singh, MD, FASRS
Louis Cai, MD
About Louis Cai, MD

Louis Cai, MD, is a board-certified ophthalmologist with specialty training in vitreoretinal surgery. He graduated summa cum laude from a combined BS/MD program at the University of Miami.

He completed his ophthalmology residency at the esteemed Wills Eye Hospital in Philadelphia. He received specialty training in vitreo­retinal surgery at Bascom Palmer Institute in Miami.

He treats medical and surgical retinal conditions including retinal tears, retinal detachments, age related macular degeneration, secondary lens placement, and diabetic retinopathy. He has coauthored over 30 papers and presentations, and has a particular interest in the intersection of artificial intelligence and medicine.

He is the producer and cohost of Straight From the Cutters Mouth, a Retina Podcast (retinapodcast.com), the longest running podcast for vitreoretinal surgeons, and is an active member of the American Academy of Ophthalmology, American Society of Retina Specialists, and the Vit Buckle Society.

Originally from Florida, Dr. Cai is fluent in English and proficient in Spanish and Mandarin Chinese. Outside of clinic, he is the cofounder of Cosign AI, a digital health startup, and enjoys spending time outdoors with his wife and two kids.

Louis Cai, MD
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