Published in Retina

A Cost-Analysis of Secondary IOLs and Pars Plana Vitrectomy

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6 min read

Join Drs. Singh and Meshkin as they discuss findings from a recent cost-analysis retrospective study of reimbursement rates for secondary IOL surgery.

In this episode of Evidence Based Retina, Rishi P. Singh, MD, FASRS, is joined by Ryan Sameen Meshkin, MD, to discuss his recent time-driven activity-based costing study of secondary intraocular lens (IOL) surgery.
The study examines whether current reimbursement adequately reflects the operative time, staffing, and resources required to deliver complex, vision-restoring vitreoretinal care.
Dr. Meshkin is a PGY4 Resident at Massachusetts Eye and Ear at Harvard Medical School and will soon move on to continue his training at the Duke Eye Center as a Vitreoretinal Surgery Fellow.

The cost of complex ophthalmologic care

Cataracts are the leading cause of blindness and are mostly considered an age-related disease. An aging population presents increased demand on healthcare systems, along with an increase in more complex cases.
Although most cataract surgeries are routine and successful, a clinically important subset of patients later require secondary IOL placement, exchange, or repositioning because of aphakia, lens dislocation, or prior surgical complications.1
“Secondary IOL surgery is a high-value surgery—it restores vision and independence, increasing the quality of life for patients. There is an increasing demand for this as we have an aging population and more folks are undergoing cataract surgery,” noted Dr. Meshkin. “With that increase, you can anticipate more complications and an additional need for secondary lenses.”
Despite the increase in complexity, reimbursement for procedures has declined over the past few decades.2 This introduces concern for patient cases requiring high-value, time-sensitive procedures that are inadequately reimbursed.
Similar reimbursement challenges have been reported across vitreoretinal surgery, including pars plana vitrectomy (PPV) for retinal detachment repair, scleral buckle surgery, and panretinal photocoagulation.3-5 Dr. Meshkin’s work has contributed to this literature through studies of academic vs. community retinal detachment surgery,6 and cost drivers in scleral buckle surgery.4
Prior work has also shown that secondary IOL surgeries frequently produce net negative margins under Medicare reimbursement.7 His recent analysis of secondary IOL procedures performed with PPV extends this work by defining procedure-specific break-even times and the proportion of cases exceeding those thresholds.8

The cost-analysis retrospective study

Dr. Meshkin and faculty mentor Dr. Nimesh Patel questioned if they could determine the actual time spent on a surgery where the procedures become unprofitable or might break even. Time-driven activity-based costing (TDABC) estimates the cost of care by assigning costs to the time, staffing, materials, and overhead required to delivery a procedure.
They published the results of their retrospective cost-analysis study in the Journal of Vitreoretinal Diseases.7 This data might inform strategies to adjust reimbursement rates or explore other cost-reducing measures.

Comparative cost-analysis study fast facts:

  • Cohort: Massachusetts Eye and Ear patient cases with secondary IOLs in conjunction with pars plana vitrectomy in 20237
    • Identified by CPT codes for IOL insertion only, IOL exchange, and IOL repositioning (all also billed with PPV)
  • Method: Time-driven activity-based costing analysis
    • Broken down on a per-minute basis
    • Compared with CMS Medicare reimbursement rates
  • Results: Break-even time was around 75 minutes, with over 85% performed in excess of that time7
    • IOL exchange cases were the most time-intensive and had the worst margins
  • Conclusion: Secondary IOLs performed with PPV are unprofitable under current reimbursement rates7

Breaking down the break-even time

“It’s clear from this study that these cases are taking far longer than what the system assumes they should be taking,” outlined Dr. Meshkin. However, depending on the clinical context or the particular practice patterns at different institutions, different variables might affect the associated costs.
For example, Dr. Meshkin says in a large hospital setting, there may actually be two surgeons working on a case. An anterior segment specialist may come in to perform the secondary IOL and they would work with a retina specialist doing the PPV. There are also a variety of secondary IOL types and different surgical techniques developed over the years as options for addressing different challenges presented with complex cases.2,9
Dr. Meshkin shared that subsequent analyses in a paper currently under review may help clarify how specific surgical techniques or IOL fixation strategies influence operative time and cost. Initial findings suggest that anterior chamber IOLs and scleral-fixated IOLs were the most costly, driven by longer operative times.

Future considerations and advocacy efforts

Dr. Meshkin acknowledges that large hospital systems like Massachusetts Eye and Ear often have greater power as an institution to negotiate better contracts with higher reimbursement rates.
Smaller facilities or independent facilities like ambulatory surgery centers may see lower reimbursement and more cases in excess of the breakeven time. The results of this hospital-based study might actually be a best-case scenario compared to those settings.
Additionally, in teaching hospitals associated with academic institutions, longer operative times may partly reflect the educational mission of training residents and fellows, an investment that benefits the future retina workforce but is not fully captured in traditional reimbursement models.
“I just came back from my first Mid-Year Forum as an AAO Advocacy Ambassador and the hope is that putting out data that shows how reimbursement does not adequately address the real cost of performing these important surgeries can have an impact on patient care,” Dr. Meshkin emphasized.

Final thoughts

In conclusion, Dr. Meshkin hopes that this study provides data to guide advocacy efforts and prove useful for specialty societies, policymakers, hospital systems, and payers when evaluating whether existing reimbursement adequately supports complex vitreoretinal procedures.
  1. Alshaikhsalama A, Talaparthy T, Aftab O, et al. Ophthalmic subspecialty medicare reimbursement decline over the past decade. Health Policy Technol. 2026;15(7):2211-8837. doi: 10.1016/j.hlpt.2026.101225.
  2. Kaufmann GT, Boucher N, Sharma C, Starr MR. Trends in Secondary Intraocular Lens Surgery among Vitreoretinal Surgeons. Ophthalmol Retina. 2023;7(11):965-971. doi: 10.1016/j.oret.2023.07.008.
  3. Pan WW, Portney DS, Mian SI, Rao RC. The cost of standard and complex pars plana vitrectomy for retinal detachment repair exceeds its reimbursement. Ophthalmol Retina. 2023;7(11):948-953. doi:10.1016/j.oret.2023.06.021.
  4. Blumenthal J, Meshkin RS, Hoyek S, et al. Operative times in scleral buckle surgery: influencing factors and cost analysis. J Vitreoretin Dis. 2024;9(1):18-25. doi:10.1177/24741264241293904.
  5. Berkowitz ST, Zhang DL, Pan WW, et al. Time-driven activity-based costing analysis of panretinal photocoagulation. Ophthalmol Retina. 2025;9(5):498-501. doi:10.1016/j.oret.2025.01.007.
  6. Meshkin RS, Blumenthal J, Hoyek S, et al. Academic versus community retinal surgery for primary retinal detachment: characteristics, duration, and value analysis of teaching modifier. Ophthalmol Retina. 2024;8(10):994-1001. doi:10.1016/j.oret.2024.04.021.
  7. Pan WW, Young C, Portney D, et al. Comparative cost analysis of secondary intraocular lens surgeries using time-driven activity-based costing. Am J Ophthalmol. 2025;273:159-166. doi:10.1016/j.ajo.2025.02.008.
  8. Meshkin RS, Hoffman SE, Chaaya MD C, et al. Time-Driven, Activity-Based Cost Analysis of Secondary Intraocular Lens Implantation. J Vitreoretin Dis. 2026 Apr 6;24741264261428752. doi:10.1177/24741264261428752.
  9. Patel KG, Shah P, Sheybani A, Apte RS. Secondary IOLs Four Ways. Retina Today. October 2022;17(7): 24-27. Accessed May 13, 2026. https://retinatoday.com/articles/2022-oct/secondary-iols-four-ways.
Rishi P. Singh, MD, FASRS
About Rishi P. Singh, MD, FASRS

Rishi P. Singh, MD, FASRS, is the Chair of the Department of Ophthalmology at Mass General Brigham, overseeing ophthalmology across Massachusetts Eye and Ear, Massachusetts General Hospital, Brigham and Women’s Hospital, and affiliated sites. He is also a Professor of Ophthalmology at Harvard Medical School.

Previously, Dr. Singh served as Vice President and Chief Medical Officer at Cleveland Clinic Martin Health in Stuart, Florida, and as a staff surgeon at the Cleveland Clinic, where he was also Professor of Ophthalmology at the Cleveland Clinic Lerner College of Medicine in Cleveland, Ohio. He received both his undergraduate degree in medical science and his medical degree from Boston University, completing his internship at Tufts University. Dr. Singh went on to complete his ophthalmology residency at the Massachusetts Eye and Ear Infirmary/Harvard Medical School and a medical and surgical vitreoretinal fellowship at the Cole Eye Institute at the Cleveland Clinic.

Dr. Singh specializes in the management of complex retinal diseases, including diabetic retinopathy, retinal vein occlusions, retinal detachment, and age-related macular degeneration. He has authored over 300 peer-reviewed publications, books, and book chapters and serves as Principal Investigator for numerous national and international clinical trials aimed at improving outcomes for patients with retinal diseases.

He is the founder and past president of the Retina World Congress, chairs some of the largest continuing medical education meetings in retina, and serves on editorial boards and review panels for major ophthalmology journals. His leadership has extended into digital innovation, having helped lead enterprise-wide implementation of clinical technologies including Epic modules, digital informed consent, and patient-facing kiosks.

Dr. Singh has received multiple accolades for his contributions to ophthalmic research and innovation, including the Alpha Omega Alpha Research Award, the American Society of Retina Specialists Young Investigator Award, and the J. Donald Gass Beacon of Sight Award. He also leads The Center for Ophthalmic Bioinformatics, a research initiative focused on leveraging big data and artificial intelligence to advance understanding and treatment of retinal disease.

Rishi P. Singh, MD, FASRS
Ryan Sameen Meshkin, MD
About Ryan Sameen Meshkin, MD

Dr. Ryan Sameen Meshkin graduated from Virginia Commonwealth University (VCU) Honors College summa cum laude in the Guaranteed Medical Admission Program with his BS in Biology and minors in Music and Chemistry. As an undergraduate, he was awarded a research fellowship grant for his project, “Preserving a Sense of Honor, Conscience, and Dignity during Medical School for the Physician-Patient Relationship.” He was selected by VCU’s President to serve on the University’s Board of Visitors. He also spent time working as a medical scribe and clinical assistant at the Mkhiwa Clinic in Manzini, Eswatini. His community engagement work was recognized with the VCU Shaaban Humanitarian Award, the highest departmental honor.

Dr. Meshkin went on to earn his MD from Harvard Medical School (HMS). He received a grant with Harvard Ophthalmology faculty Ankoor Shah, MD, PhD, and Grayson Armstrong, MD, MPH, to create a narrated surgical video library curriculum to facilitate deeper learning and active learner engagement during medical student ophthalmology clinical rotations. The project has grown to involve medical student education leaders across the country, and has received the support of the Association of University Professors of Ophthalmology (AUPO)/American Academy of Ophthalmology (AAO) medical education taskforce to publish the curriculum on the AAO medical student website. In collaboration with Alice Lorch, MD, MPH, and Dr. Armstrong, he helped secure an Alcon Foundation grant to launch a pilot program to provide comprehensive ophthalmology care and disease screenings to underserved Boston communities lacking adequate access to eye care. This pilot program was selected to receive the Mass General Brigham (MGB) United Against Racism Grant, which seeks to address and eliminate racism within MGB by supporting partnerships with community organizations to advance social justice and equity goals.

Devoted to community service, Dr. Meshkin pursued a 5th year during medical school to serve as part of a grassroots community-building program in Chelsea, MA, inspiring young people to reach their full potential through service to their neighborhood in the Junior Youth Spiritual Empowerment Program. As part of Mass Eye and Ear’s Inclusion, Diversity, and Equity initiatives, he spearheads opportunities for Chelsea High School students to explore health-related careers. At graduation, he was awarded Harvard Medical School’s John D. and Gretchen H. Bullock Ophthalmology Award as well as the Harvard Community Service Award.

Dr. Meshkin’s work has been published in peer-reviewed journals, such as Journal of Academic Ophthalmology, Cornea, Journal of Glaucoma, British Journal of Ophthalmology, and Translational Vision Science and Technology. He has presented his work at conferences such as AAO, American Society of Retina Specialists, AUPO, and Association for Research in Vision and Ophthalmology.

He completed a Transitional Year Internship at Newton Wellesley Hospital as part of Harvard Ophthalmology’s four-year integrated residency program, where he received the Excellence in Medical Student Education award for outstanding teaching of medical students on their clerkships.

Ryan Sameen Meshkin, MD
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